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Women use creatine differently from men, survey reveals (opens in a new tab)

news-medical.net · 2026-09-10

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Mostly supported

Mostly supported.

The claims we could check match the study, but some claims were not covered by the evidence reviewed.

  • 4 supported
  • 1 not covered

Checked against the study summary. The full text wasn't available, so some details couldn't be settled either way.

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Mostly supported

Every claim we could check holds up. Four of five claims match the study. This overall rating is based only on the claims we could check. One claim the study doesn't address.

  • 4 supported
  • 1 not covered
Open claim evidence
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The source study

Creatine Use Among Women Across Reported Duration-of-Use Groups: A Platform-Based Cross-Sectional Survey of Supplementation Behaviors, Motivations, Knowledge, and Experiences

Nutrients · 2026
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The 2 papers the story cites

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  • The study this story reportsmentioned without context

    Creatine Use Among Women Across Reported Duration-of-Use Groups: A Platform-Based Cross-Sectional Survey of Supplementation Behaviors, Motivations, Knowledge, and Experiences

    Nutrients · 2026

  • The study this story reportspresented as the new finding

    Creatine Use Among Women Across Reported Duration-of-Use Groups: A Platform-Based Cross-Sectional Survey of Supplementation Behaviors, Motivations, Knowledge, and Experiences

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What the story left out

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  • Within-women duration analysis: among women, knowledge alignment was higher at longer reported durations, and lower knowledge alignment among shorter-duration women reflected greater uncertainty rather than greater myth endorsement.

    The story focuses on between-gender knowledge and confidence differences, but it does not clearly report the women-only duration gradient in knowledge alignment or the uncertainty-versus-myth-endorsement interpretation from the abstract-level profile.

    From Cross-sectional women-only subgroup analysis (platform-based convenience survey)

  • Information-source findings: six of seven information sources differed by gender, and information sources were also compared across women’s duration-of-use bands.

    The story presentation does not include the paper’s information-source results or methods, despite these being part of the profile’s primary/secondary contributions.

    From Cross-sectional women-only subgroup analysis (platform-based convenience survey); Cross-sectional comparative analysis (

5 things the story did carry across
  • Primary duration-of-use representation finding: women were more represented in shorter reported creatine-use duration categories and much less represented in the 3+ year group, based on age-adjusted cross-sectional modeling.
  • Gender differences in supplementation goals: women were less likely than men to report athletic performance and more likely to report healthy aging, in age- and duration-adjusted pooled analyses.
  • Gender differences in knowledge alignment and the knowledge-by-gender confidence interaction.
  • Core design and sample context: cross-sectional supplement-platform convenience survey of current or recent creatine users, with 2094 analyzed participants, 1055 women, 1039 men, and approximately 2.0% response rate.
  • Interpretation-changing limitations: cross-sectional design precludes causal inference; convenience sampling and low response rate limit generalizability; self-report creates measurement-error or misclassification risk; potential residual confounding/unmeasured factors remain.
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study summary

Lead result

human in vivo

1Lead resulthuman in vivoCharacterize how women are represented across reported creatine duration-of-use categories (vs men), using age-adjusted models and trend testing in a cross-sectional supplement-platform survey of current/recent users.Cross-sectional convenience survey; age-adjusted logistic regression of categorical duration bandsExpand

In plain English

In a cross-sectional, supplement-platform convenience survey of 2094 current or past-12-month creatine users (1055 women, 1039 men; mean age 53 y), the authors evaluated representation of women across six ordered duration-of-use bands using an age-adjusted logistic regression with duration as a categorical factor and reported a Cochran–Armitage trend test. Women made up 50.0–63.9% of respondents in duration categories below three years but only 19.7% of those reporting 3+ years. In the primary age-adjusted analysis, gender composition differed strongly across duration categories (global p < 0.001); relative to the 3+ year group, the odds of identifying as a woman were 3.9- to 7.5-fold higher in every shorter-duration category.

Key findings

  • Women were overrepresented in shorter reported duration-of-use categories and underrepresented in the longest (3+ year) category: women made up 50.0–63.9% of respondents in categories <3 years but only 19.7% in the 3+ year group; age-adjusted categorical analysis showed a strong difference across duration groups (global p < 0.001).Odds ratios for identifying as a woman (each shorter duration group vs 3+ years): 3.9–7.5
“In a cross-sectional, supplement-platform convenience survey (approximately 2.0% response rate; a secondary analysis of a previously reported cohort), 2094 current or recent creatine users (1055 women, 1039 men) reported duration of use”
What this piece can’t prove
  • Convenience sampling from a supplement-platform cohort and low reported response rate (~2.0%) limit generalizability.
  • Self-reported gender and duration-of-use categories may be subject to misclassification.
  • Cross-sectional secondary analysis cannot determine why women are less represented in the 3+ year group (no causal inference).
  • Abstract reports age-adjustment for the primary analysis; other potential confounders are not described in this appraisal unit.
2human in vivoAmong women users, compare motivations/goals, information sources, and knowledge-alignment patterns across duration-of-use bands (including adjusted association of knowledge alignment with duration and characterization of uncertainty vs myth endorsement).Cross-sectional women-only subgroup analysis (platform-based convenience survey)Expand

In plain English

In a women-only subgroup analysis of a platform-based cross-sectional supplement survey (n=1,055 women reporting current or past-12-month creatine use), the authors compared reported supplementation goals and information sources across six ordered duration-of-use bands using unadjusted homogeneity tests, and evaluated a five-item creatine knowledge-alignment battery across duration bands with an ordered trend test and multivariable adjustment (age, BMI, physical activity). The abstract reports that knowledge alignment was higher at longer reported durations and that lower knowledge alignment among shorter-duration women reflected greater uncertainty rather than endorsement of myths; specific within-women results for goals and information sources by duration are not detailed in the abstract.

Key findings

  • Among women creatine users, knowledge-alignment scores (five-item battery) were higher at longer reported durations of use and the association with duration persisted after adjustment for age, BMI, and physical activity.Adjusted global categorical test p < 0.001
  • Lower knowledge alignment among shorter-duration women was characterized in the abstract as reflecting greater uncertainty (i.e., more 'don't know' responses) rather than greater endorsement of creatine-related myths.
“Among women, goals and information sources were compared across duration-of-use bands using unadjusted tests of homogeneity, and knowledge alignment was evaluated using an ordered trend test.”
What this piece can’t prove
  • Cross-sectional, observational design precludes causal inference regarding duration and knowledge.
  • Platform-based convenience sample with a low reported overall response rate (~2.0%) and secondary analysis of a previously reported cohort, introducing potential selection bias and limited generalizability.

2 further details could not be confirmed from the summary.

3human in vivoEstimate gender differences (pooled across duration groups) in goals, information sources, and knowledge alignment; test gender × duration interactions for goals and information sources with multiplicity control.Cross-sectional comparative analysis (gender)Expand

In plain English

Pooled, age- and duration-adjusted comparisons between women and men respondents in a cross-sectional supplement-platform survey (n=2094; 1055 women, 1039 men) found gender differences in supplementation goals, information sources, and knowledge-alignment. Models were adjusted for age and reported duration of creatine use, multiplicity was controlled within outcome domains using Benjamini–Hochberg, and gender × duration interactions were tested for goals and information sources.

Key findings

  • Women were less likely than men to report athletic performance as a supplementation goal in age- and duration-adjusted models.Adjusted percentages: women 37.5% vs men 50.2%
  • Women were more likely than men to report healthy aging as a supplementation goal (pooled, age- and duration-adjusted).
“Gender differences were estimated in age- and duration-adjusted models, pooled across duration groups, with Benjamini–Hochberg correction within domain; gender × duration interactions were tested for the goal and information-source outcomes.”
What this piece can’t prove
  • Cross-sectional, convenience sample from a supplement platform with a low response rate (~2.0%), limiting representativeness and precluding causal inference.

2 further details could not be confirmed from the summary.

4human in vivoModel self-rated confidence as a function of knowledge alignment, gender, and their interaction (gender difference in confidence conditional on observed knowledge).cross-sectional regression modeling (knowledge × gender interaction)Expand

In plain English

In a cross-sectional supplement-platform survey, self-rated confidence was modeled as a function of knowledge-alignment score, participant gender, and their interaction. The model found a significant knowledge-by-gender interaction (p = 0.012): women reported progressively lower self-rated confidence than men as observed knowledge-alignment scores increased, with an adjusted difference of −0.38 points at the highest observed knowledge score.

Key findings

  • Regression of self-rated confidence on knowledge alignment, gender, and their interaction showed a significant interaction (p = 0.012): women reported progressively lower self-rated confidence than men as knowledge-alignment scores increased; adjusted difference −0.38 points at the highest observed knowledge score.interaction p = 0.012; adjusted difference −0.38 points at highest knowledge score
“Self-rated confidence was modeled as a function of knowledge, gender, and their interaction.”
What this piece can’t prove
  • Cross-sectional design—associations only, no causal inference.
  • Convenience, platform-based sample with low response rate (~2.0%) and secondary analysis of a previously reported cohort—limited generalizability.
  • Abstract does not provide full measurement or modeling details (e.g., scale ranges, model covariates beyond the interaction specification).
  • Possible residual confounding and self-report measurement biases.
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Creatine Use Among Women Across Reported Duration-of-Use Groups: A Platform-Based Cross-Sectional Survey of Supplementation Behaviors, Motivations, Knowledge, and Experiences

Nutrients · 2026

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Papers considered

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Crossref, PubMed, Europe PMC · 15 candidate papers

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Creatine Use Among Women Across Reported Duration-of-Use Groups: A Platform-Based Cross-Sectional Survey of Supplementation Behaviors, Motivations, Knowledge, and Experiences

Nutrients · 2026 · Crossref

And 9 more candidates considered.