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What happened to people’s brains when they ate tomato paste every day (opens in a new tab)

nypost.com · 2026-09-20

Short answerEvidenceSource

Short answer

Mostly not supported

Mostly not supported.

3 claims go further than the study. One other point was not covered by the paper.

  • 1 supported
  • 3 overstated
  • 1 not covered

Checked against the study summary. The full text wasn't available, so some details couldn't be settled either way.

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NewsLink checks it

Mostly not supported

Three of five claims overstate the study. One of five checks out. One claim the study doesn't address.

  • 1 supported
  • 3 overstated
  • 1 not covered
Open claim evidence
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Source paper

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5 claims in this story

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What the story left out

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  • Randomized two-period crossover clinical trial in healthy adults aged 40–55, with two 3-month intervention periods separated by a 1-month washout.

    The story reflects that this was a clinical trial in healthy middle-aged adults, but it appears to describe parallel groups rather than the material crossover design and does not mention the washout.

    From Randomized two-period crossover dietary intervention

3 things the story did carry across
  • Cognitive testing found reported improvements in selective attention, processing speed, and associative memory after tomato intake compared with the lycopene-restricted control period.
  • Resting-state fMRI showed network connectivity changes, including reduced frontoparietal and auditory connectivity during the tomato period and reductions in the dorsal attention network during the control period.
  • Clinical relevance and durability of the cognitive changes are not established in the abstract-level profile.
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study summary

Lead result

human in vivo

1Lead resulthuman in vivoDetermine whether daily concentrated tomato paste intake improves cognitive performance in healthy middle-aged adults versus a lycopene-restricted control diet in a randomized two-period crossover trial.Randomized two-period crossover dietary interventionExpand

In plain English

Randomized two-period crossover trial in 47 healthy adults (age 40–55; 42 completers) comparing daily concentrated tomato paste (0.5 g/kg body weight) for 3 months versus a lycopene-restricted control diet, with a 1-month washout. Cognitive performance was assessed with validated neuropsychological tests (d2-R, Face-Name Associative Memory Exam, Modified Wisconsin Card Sorting Test); plasma lycopene and BDNF and resting-state fMRI were measured as secondary/mechanistic endpoints. Compared with the control diet, tomato intake was reported to improve selective attention (concentration performance +7.2 points), processing speed (+8.3 points), and associative memory (face–name matching +0.8 points). Plasma BDNF showed a borderline mean increase (15.2 ng/mL) with tomato intake. Resting-state fMRI indicated changes in functional connectivity, including reduced connectivity in frontoparietal and auditory networks during the tomato period (with reductions in the dorsal attention network observed during the control period).

Key findings

  • Daily concentrated tomato paste intake improved selective attention and processing speed compared with a lycopene-restricted control diet.Concentration performance +7.2 points; processing speed +8.3 points
  • Tomato intake improved associative memory as measured by face–name matching.+0.8 points (face–name matching)
“A randomized, two-period crossover trial ... was conducted in 47 healthy adults aged 40-55 years assigned to two 3-month interventions separated by a 1-month washout”
What this piece can’t prove

4 further details could not be confirmed from the summary.

2human in vivoAssess whether tomato paste intake alters circulating biomarkers (plasma lycopene exposure and plasma BDNF) relative to the control diet within the crossover trial.randomized two-period crossover dietary interventionExpand

In plain English

Randomized two-period crossover trial in healthy adults (age 40–55) assessed plasma lycopene and plasma BDNF after 3-month periods of daily concentrated tomato paste (0.5 g/kg body weight) versus a lycopene-restricted control diet, separated by a 1-month washout. Plasma BDNF showed a borderline increase with tomato intake (mean difference 15.2 ng/mL). Plasma lycopene was measured but the abstract does not report the magnitude/direction of change.

Key findings

  • Plasma BDNF exhibited a borderline increase during the tomato intake period compared with the lycopene-restricted control period.Mean difference 15.2 ng/mL (described as borderline increase in abstract)
  • Plasma lycopene was measured as a biomarker of exposure during the trial, but the abstract does not report the effect of the tomato intervention on plasma lycopene levels.
“... alongside plasma lycopene and BDNF”
What this piece can’t prove

4 further details could not be confirmed from the summary.

3human in vivoExplore whether tomato paste intake modulates resting-state functional brain connectivity (fMRI network connectivity changes) versus control within the crossover trial.randomized crossover dietary interventionExpand

In plain English

In this randomized, two-period crossover trial in healthy middle-aged adults, resting-state fMRI was used to compare functional brain network connectivity after daily concentrated tomato paste intake versus a lycopene-restricted control period. The abstract reports that tomato intake was associated with changes in resting-state networks, specifically reduced connectivity in frontoparietal and auditory networks, whereas the control period was associated with reductions in the dorsal attention network. Imaging-methodologic details, statistical parameters, and effect sizes for connectivity changes are not provided in the abstract.

Key findings

  • Tomato intake was associated with reduced resting-state functional connectivity in frontoparietal and auditory networks compared with the control period.
  • During the control (lycopene-restricted) period, reductions were observed in the dorsal attention network.
“... and resting-state functional magnetic resonance imaging (fMRI).”
What this piece can’t prove
  • Moderate sample size reported (47 randomized, 42 completed); abstract does not specify how many participants contributed usable imaging data after quality control.
  • Crossover design includes a 1-month washout as reported, but the abstract does not report tests for carryover or period effects specific to imaging outcomes.

2 further details could not be confirmed from the summary.

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Papers considered

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Crossref, PubMed, Europe PMC · 17 candidate papers

And 11 more candidates considered.