Several possible studies
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Trial supports MRI surveillance over preventive brain radiation in small-cell lung cancer (opens in a new tab)
medicalxpress.com · 2026-09-12
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Several possible studiesNo clear answer.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
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Trial supports MRI surveillance over preventive brain radiation in small-cell lung cancer
medicalxpress.com · 2026-09-12
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Several studies could be the source of this story.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
Open claim evidenceSearch result
Several studies could fit.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
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What the story asserts. With no source study, there is nothing to check these against.
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Claim 1 of 6Not checkedResults from the international phase 3 SWOG S1827 MAVERICK trial show that brain MRI surveillance alone improved cognitive failure-free survival compared with MRI surveillance plus prophylactic cranial irradiation (PCI) in patients with small-cell lung cancer (SCLC).View evidenceHide evidence
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 2 of 6Not checkedThe findings support MRI surveillance alone as the standard of care for patients with SCLC, according to research presented at the IASLC 2026 World Conference on Lung Cancer.View evidenceHide evidence
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 3 of 6Not checkedThe trial enrolled 304 patients with limited-stage or extensive-stage SCLC who had completed initial therapy and had no brain metastases on MRI before enrollment, and it randomized them to MRI surveillance alone or MRI surveillance plus PCI.View evidenceHide evidence
As stated304 patients
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 4 of 6Not checkedAt a median follow-up of 22 months among living patients, MRI surveillance alone reduced the risk of cognitive failure or death by 40% versus MRI plus PCI (HR 0.60; 90% CI 0.46–0.78; p = 0.001).View evidenceHide evidence
As stated40%
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 5 of 6Not checkedA preliminary overall survival analysis after 128 deaths showed no apparent difference between the treatment strategies (HR 0.90; 90% CI 0.67–1.20), and brain metastasis-free survival was also not significantly different (HR 1.25; 90% CI 0.95–1.66).View evidenceHide evidence
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 6 of 6Not checkedSerious treatment-related adverse events were less frequent with MRI surveillance alone than with MRI surveillance plus PCI, with grade 3–5 adverse events in 0.8% versus 7.9% of patients, and one grade 5 encephalopathy event in the PCI group.View evidenceHide evidence
As stated0.8% vs 7.9%
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Method layer
No single source study was found.
NewsLink still surfaces nearby research so you can inspect the field instead of a single paper.
Nearby research
No exact source, but these papers are close.
PubMed, Europe PMC, Crossref · 15 candidate papers
BraMARS: An Interpretable Histopathology-Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited-Stage SCLC.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · PubMed, Europe PMC
Randomized trials on prophylactic cranial irradiation for patients with small cell lung cancer in complete remission
Lung Cancer · 1994 · Crossref
Comparative Effectiveness and Safety of Prophylactic Cranial Irradiation Versus Magnetic Resonance Imaging Surveillance in Limited-Stage Small Cell Lung Cancer.
Practical Radiation Oncology · 2026 · PubMed, Europe PMC
Small-Cell Carcinoma of the Bladder With Concurrent High-Grade Prostate Cancer: A Case Report and Review of the Literature.
Cureus · 2026 · PubMed
Good quality long term survival without prophylactic cranial irradiation (PCI) in small cell lung cancer (SCLC)
Lung Cancer · 1986 · Crossref
And 10 more candidates considered.