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This Diet And Exercise Combination Put Early-Onset Diabetes Into Remission in Half of Participants : ScienceAlert (opens in a new tab)
sciencealert.com · 2026-10-16
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The story
This Diet And Exercise Combination Put Early-Onset Diabetes Into Remission in Half of Participants : ScienceAlert
sciencealert.com · 2026-10-16
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Open claim evidenceThe source study
Low energy diet plus supervised exercise vs. usual care alone in people with early-onset type 2 diabetes (RESET for Remission): a randomised, open-label, blinded-endpoint efficacy trial
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Claim 1 of 5Not checkedResearchers in the UK and Canada identified a way to put more than 50 percent of patients with early-onset type 2 diabetes into remission using a low-calorie diet and a supervised exercise program.View evidenceHide evidence
As statedmore than 50 percent
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The source study was found, but this claim couldn't be checked against it.
Claim 2 of 5Not checkedThe trial included 96 participants with early-onset type 2 diabetes and obesity across three centers in Canada and the UK, and about half were randomized to usual life while the other half received the low-energy diet and exercise intervention.View evidenceHide evidence
As stated96 participants
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The source study was found, but this claim couldn't be checked against it.
Claim 3 of 5Not checkedAt 24 weeks, remission occurred in 27 of 50 participants in the intervention group versus 2 participants in the control group, a difference of 50 percent, and it happened without glucose-lowering medicine.View evidenceHide evidence
As stated27 out of 50; two participants; 50 percent
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The source study was found, but this claim couldn't be checked against it.
Claim 4 of 5Not checkedParticipants in the intervention group lost substantial fat mass while preserving muscle mass and strength, and they also showed improved cardiovascular measures including a 10.3 percent increase in respiratory fitness relative to body mass, lower resting blood pressure and heart rate, and a healthier left-ventricular shape and structure.View evidenceHide evidence
As stated10.3 percent increase
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Claim 5 of 5Not checkedParticipants reported less diabetes-related distress and better quality of life, but the article says it remains unclear how long the benefits last and whether diet or exercise played the larger role.View evidenceHide evidence
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Method layer
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Low energy diet plus supervised exercise vs. usual care alone in people with early-onset type 2 diabetes (RESET for Remission): a randomised, open-label, blinded-endpoint efficacy trial
The Lancet Regional Health - Americas · 2026
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Papers considered
The selected paper, plus nearby candidates.
Crossref, PubMed, Europe PMC · 16 candidate papers
Low energy diet plus supervised exercise vs. usual care alone in people with early-onset type 2 diabetes (RESET for Remission): a randomised, open-label, blinded-endpoint efficacy trial
The Lancet Regional Health - Americas · 2026 · Crossref
BBS10-related Bardet-Biedl syndrome with an atypical presentation of diabetes mellitus: A case report.
Experimental and Therapeutic Medicine · 2026 · PubMed
A food‐based, low‐energy, low‐carbohydrate diet for people with type 2 diabetes in primary care: A randomized controlled feasibility trial
Diabetes, Obesity and Metabolism · 2020 · Crossref
A case report of young-onset type 2 diabetes patient with severe metabolic dysregulation carrying an LRP6 variant.
2026 · Europe PMC
Type A Insulin Resistance Syndrome Due to a Pathogenic Variant in the INSR Gene.
Irish Medical Journal · 2026 · PubMed
The Emphasis on Remission of Type 2 Diabetes through Diet
Interventions in Obesity & Diabetes · 2023 · Crossref
And 10 more candidates considered.