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Study identifies brain mechanism behind pregnancy-related food cravings (opens in a new tab)

news-medical.net · 2026-09-18

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Claim 1 of 7Not checkedResearchers identified a brain mechanism that may help explain how pregnancy changes the motivation to seek certain highly palatable foods.View evidenceHide evidence

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Claim 2 of 7Not checkedIn a collaborative study led by Dr. Yanlin He with Dr. Pingwen Xu and Dr. Chunmei Wang, serotonin-producing neurons in the dorsal raphe nucleus became less active during pregnancy, increasing food-craving-like behavior in animal models.View evidenceHide evidence

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Claim 3 of 7Not checkedActivity of the SK3 potassium ion channel increased in serotonin neurons during pregnancy, and increased SK3 activity reduced the firing of those neurons.View evidenceHide evidence

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Claim 4 of 7Not checkedRemoving SK3 specifically from these serotonin neurons prevented the pregnancy-associated reduction in neuronal activity and substantially reduced food-craving-like behavior.View evidenceHide evidence

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Claim 5 of 7Not checkedIncreasing SK3 activity in nonpregnant females produced neuronal and food-seeking changes resembling those seen during pregnancy.View evidenceHide evidence

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Claim 6 of 7Not checkedThe study also identified a dorsal raphe serotonin pathway to the ventral tegmental area; activating the pathway reduced food-craving-like behavior in pregnant animals, while inhibiting it increased the behavior in nonpregnant animals.View evidenceHide evidence

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Claim 7 of 7Not checkedThe authors say the findings may improve understanding of pregnancy-related food cravings and excessive weight gain, but caution that the work is based on animal models and that direct serotonin manipulation during pregnancy could carry risks.View evidenceHide evidence

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Serotonin neurons in the dorsal raphe control food-craving-like behavior during pregnancy in mice

Nature Neuroscience · 2026

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Crossref, Europe PMC, PubMed · 41 candidate papers

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Serotonin neurons in the dorsal raphe control food-craving-like behavior during pregnancy in mice

Nature Neuroscience · 2026 · Crossref

Source (opens in a new tab)
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Author response for "Fatty Acid from Recycled Waste Cooking Oil as Phase Change Material for Thermal Storage System"

2026 · Crossref

Source (opens in a new tab)

And 35 more candidates considered.