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Six-gene scoring system could help predict leukemia survival (opens in a new tab)

medicalxpress.com · 2026-10-23

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Short answer

Source study unconfirmed

Study not confirmed.

The search did not establish a source study for this article. Its claims remain unverified; this does not mean they are incorrect.

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The search identified related research but did not establish a single source study. Related papers are provided for context, not as verification of the article's claims.

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Source study unconfirmed.

The search identified related research but did not establish a single source study. Related papers are provided for context, not as verification of the article's claims.

Source paper

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39 candidate papers

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These papers appeared in the search for the story’s source. None was confirmed as a direct match. Inclusion here does not mean a paper supports or contradicts the story, or that its full text was reviewed.

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Claim 1 of 7Not checkedThe activity of six different genes can help determine survival in patients with acute myeloid leukemia (AML), according to a study published in Science Advances.View evidenceHide evidence

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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.

Claim 2 of 7Not checkedResearchers at the Center for Genomic Regulation in Barcelona created a six-gene scoring system by moving between laboratory experiments with mice and patient records, looking for genes that behaved consistently in both.View evidenceHide evidence

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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.

Claim 3 of 7Not checkedThe six genes reportedly reliably predict patient survival: CARMIL1, HOPX and ALDH1A1 were more active in patients with poor outcomes, while CALR, STAR and PHF19 were less active.View evidenceHide evidence

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Claim 4 of 7Not checkedThe combined activity of the six genes, called PHFScore, divided patients into groups with sharply different survival prospects.View evidenceHide evidence

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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.

Claim 5 of 7Not checkedAmong younger adults treated for AML, those with the lowest levels of PHF19 survived for less time than those with the highest levels and were less likely to go into remission after standard chemotherapy; fewer than half responded versus up to 85% of those with the highest levels.View evidenceHide evidence

As statedfewer than half vs up to 85%

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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.

Claim 6 of 7Not checkedThe researchers say the score could contribute to future prognostic tests and that measuring six genes may be simpler and cheaper than reading a broader genetic profile.View evidenceHide evidence

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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.

Claim 7 of 7Not checkedSome of the genes have not previously been linked to blood cancer and may be potential new therapeutic targets.View evidenceHide evidence

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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.

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Method layer

Study not confirmed.

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Candidate papers, not confirmed sources.

Crossref, PubMed · 39 candidate papers

Candidate

Las Estrategias de Comunicación Publicitaria Digital en Instagram y su Influencia en la Decisión de Compra de los Estudiantes de la Universidad Tecnológica Ecotec

Revista De Finanzas · 2026 · Crossref

Source (opens in a new tab)
Candidate

The distal humerus of Pliobates cataloniae (Primates: Pliopithecoidea): functional and locomotor inferences

Journal of Mammalian Evolution · 2026 · Crossref

Source (opens in a new tab)
Candidate

Author response for "The ray-finned fish blackbox: Unprecedented morphological diversity and the interplay between brain and endocast"

2026 · Crossref

Source (opens in a new tab)

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