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Scientists Studied 1,300 Cancer Patients, Then Found a Pattern in the Gut - Newsweek (opens in a new tab)
newsweek.com · 2026-09-24
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Scientists Studied 1,300 Cancer Patients, Then Found a Pattern in the Gut - Newsweek
newsweek.com · 2026-09-24
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Microbiome signatures linked to cancer and treatment adverse events in a real-world cohort
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Claim 1 of 7Not checkedAfter studying stool samples from more than 1,300 cancer patients, scientists uncovered distinct gut microbiome patterns tied to different cancers.View evidenceHide evidence
As statedmore than 1,300 cancer patients
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Claim 2 of 7Not checkedResearchers from Mayo Clinic analyzed samples from 1,364 cancer patients across a range of cancer types, stages and treatments as part of the Mayo Clinic Cancer Microbiome Cohort study, published in Cell.View evidenceHide evidence
As stated1,364 cancer patients
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Claim 3 of 7Not checkedScientists found unique microbiome signatures associated with five major cancer groups, while also identifying notable differences in patients diagnosed at younger ages.View evidenceHide evidence
As statedfive major cancer groups
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Claim 4 of 7Not checkedPatients aged 50 and under with colorectal cancer had higher levels of lactate and greater amounts of Veillonella parvula, while younger breast cancer patients showed changes across 64 bacterial species and lower levels of primary bile acids.View evidenceHide evidence
As stated50 and under; 64 bacterial species
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Claim 5 of 7Not checkedThe findings do not yet explain why breast and colorectal cancers are becoming more common among younger adults, but they may provide biomarkers and mechanistic leads to test in independent clinical cohorts and preclinical models.View evidenceHide evidence
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Claim 6 of 7Not checkedThe study suggested the microbiome could help predict which patients are more likely to experience treatment side effects, especially diarrhea among patients receiving 5-fluorouracil, but not among patients receiving carboplatin.View evidenceHide evidence
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Claim 7 of 7Not checkedResearchers additionally identified gut bacteria associated with survival outcomes in colorectal, liver and intrahepatic bile duct, ovarian and prostate cancers, as well as melanoma.View evidenceHide evidence
As statedfive cancer types plus melanoma
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Microbiome signatures linked to cancer and treatment adverse events in a real-world cohort
Cell · 2026
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Papers considered
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Crossref, PubMed, Europe PMC · 16 candidate papers
Microbiome signatures linked to cancer and treatment adverse events in a real-world cohort
Cell · 2026 · Crossref
Gut microbiota characteristics of gastric cancer patients across distinct pathological stages and their associations with tumor and paratumor mucosal microbiota.
Frontiers in Cellular and Infection Microbiology · 2026 · PubMed
Stool and Blood Sampling for Early Detection of Colorectal Cancer
Early Diagnosis and Treatment of Cancer Series: Colorectal Cancer · 2011 · Crossref
A functional immune-based platform for donor-recipient matching in faecal microbiota transplantation for inflammatory bowel disease.
2026 · Europe PMC
Baseline characteristics of participants recruited into the COLO-COHORT study: a UK-wide resource for colorectal cancer prevention.
BMJ Open Gastroenterology · 2026 · PubMed
Early age onset colorectal cancer
Advances in Cancer Research · 2021 · Crossref
And 10 more candidates considered.