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Scientists Reveal What Happens When You Switch From a Low-Carb to a High-Carb Diet : ScienceAlert (opens in a new tab)
sciencealert.com · 2026-09-09
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Scientists Reveal What Happens When You Switch From a Low-Carb to a High-Carb Diet : ScienceAlert
sciencealert.com · 2026-09-09
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- Also referencedmentioned without context
Efficacy of long‐term low carbohydrate diets for patients with type 2 diabetes: A systematic review and meta‐analysis
Journal of Diabetes Investigation · 2024
- Also referencedpresented as the new finding
10.1016/j.cpblue.2026.100122
- Also referencedmentioned without context
Adipsin in the pathogenesis of cardiovascular diseases
Vascular Pharmacology · 2024
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Claim 1 of 6Not checkedIn a new study in Cell Press Blue, scientists explored what happens when people come off a low-carb diet and resume eating foods high in carbohydrates.View evidenceHide evidence
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Claim 2 of 6Not checkedThe study involved 54 overweight or obese adults without cardiovascular disease or diabetes who first ate a very-low-carbohydrate diet during a weight-loss run-in and then, after losing about 15 percent of their weight, were randomized for 10 weeks to continue very-low-carb eating or switch to one of two high-carbohydrate diets.View evidenceHide evidence
As stated54 participants; ~15% weight loss; 10 weeks
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Claim 3 of 6Not checkedThe two high-carb diets had the same macronutrient mix, but one got 20 percent of its energy from starch in refined grains and the other got the same proportion from added sugar.View evidenceHide evidence
As stated57% carbohydrate, 25% fat, 18% protein; 20% of total energy from starch or added sugar
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Claim 4 of 6Not checkedBlood tests from about 40 participants suggested the high-starch diet triggered more inflammation and immune activation than the other two groups, including higher circulating adipsin and increased activation of CD4+ T cells and neutrophils.View evidenceHide evidence
As statedapproximately 40 participants
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Claim 5 of 6Not checkedA mouse experiment found that animals fed maltodextrin derived from starch after fasting showed increased immune activity, which the story says further suggests starch can affect the immune system.View evidenceHide evidence
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Claim 6 of 6Not checkedThe researchers caution that the high-sugar group had the lowest immune activation, but they say that should not be interpreted as evidence that high sugar intake is good for you.View evidenceHide evidence
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Crossref, PubMed, Europe PMC · 17 candidate papers
Efficacy of long‐term low carbohydrate diets for patients with type 2 diabetes: A systematic review and meta‐analysis
Journal of Diabetes Investigation · 2024 · Crossref
Adipsin in the pathogenesis of cardiovascular diseases
Vascular Pharmacology · 2024 · Crossref
Randomized double-blind placebo-controlled trial of powdered Brassica rapa ethanol extract on alteration of body composition and plasma lipid and adipocytokine profiles in overweight subjects.
Journal of Medicinal Food · 2013 · PubMed
Very Low‐Carbohydrate versus Isocaloric High‐Carbohydrate Diet in Dietary Obese Rats
Obesity · 2006 · Crossref
Supplementation with Probiotic Camel Milk Powder Improves Serum Glucose and Cholesterol as Well as the Related Cytokines in Patients with Type 2 Diabetes Mellitus.
2025 · Europe PMC
And 12 more candidates considered.