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Scientists Find a Subtle Clue to ADHD Hidden in The Eyes : ScienceAlert (opens in a new tab)
sciencealert.com · 2026-09-13
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Scientists Find a Subtle Clue to ADHD Hidden in The Eyes : ScienceAlert
sciencealert.com · 2026-09-13
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Open claim evidenceThe source study
Trial-level pupil dynamics reflect attention-related variability and medication-associated modulation in ADHD
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Claim 1 of 6Not checkedA new study suggests the rhythm of pupil changes may be subtly different in children with ADHD.View evidenceHide evidence
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Claim 2 of 6Not checkedThe researchers reanalyzed existing eye-tracking data from 50 children aged 10 to 12 in Chile, including 28 with combined-type ADHD and 22 without a neurodevelopmental diagnosis.View evidenceHide evidence
As stated50 children; 28 ADHD, 22 controls
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Claim 3 of 6Not checkedAfter accounting for age, IQ, and task difficulty, the model estimated about 23 percent greater trial-to-trial variability in pupil responses in unmedicated children with ADHD than in controls.View evidenceHide evidence
As statedabout 23 percent greater
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Claim 4 of 6Not checkedAmong the unmedicated children with ADHD, greater pupil variability was associated with lower task accuracy.View evidenceHide evidence
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Claim 5 of 6Not checkedIn the 17 children with ADHD who were tested both off and on methylphenidate, medication was associated with stronger pupil responses, less fluctuation between rounds, and a response pattern more like the control group.View evidenceHide evidence
As stated17 children
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Claim 6 of 6Not checkedThe researchers and article caution that pupil size is an indirect signal, the study was small and based on existing data, and it is too early to consider pupil measurements a clinical diagnostic tool.View evidenceHide evidence
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Trial-level pupil dynamics reflect attention-related variability and medication-associated modulation in ADHD
Scientific Reports · 2026
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Papers considered
The selected paper, plus nearby candidates.
Crossref, PubMed, Europe PMC · 16 candidate papers
Trial-level pupil dynamics reflect attention-related variability and medication-associated modulation in ADHD
Scientific Reports · 2026 · Crossref
Eye-Tracking and Borderline Personality Disorder: A Systematic Review.
Brain Sciences · 2026 · PubMed, Europe PMC
Working memory in children with attention-deficit/hyperactivity disorder (ADHD): the impact of methylphenidate (MPH).
Http://isrctn.org/> · 2012 · Crossref
Temporal variability in pupillary asymmetry reflects ADHD-related traits in preschool and early school-aged children.
Frontiers in Cognition · 2026 · PubMed, Europe PMC
Anxiety, Methylphenidate Response, and Working Memory in Children With ADHD
Journal of Attention Disorders · 2008 · Crossref
Ocular structural parameters in children with attention-deficit/hyperactivity disorder: a case-control study of drug-naïve and methylphenidate-treated patients.
2026 · Europe PMC
And 10 more candidates considered.