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Running distance is associated with how female runners distribute their daily energy expenditure (opens in a new tab)

medicalxpress.com · 2026-10-28

Short answerEvidenceSource

Short answer

Mostly supported

Mostly supported.

The claims we could check match the study, but some claims were not covered by the evidence reviewed.

  • 5 supported
  • 1 not covered

Checked against the study summary. The full text wasn't available, so some details couldn't be settled either way.

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NewsLink checks it

Mostly supported

Every claim we could check holds up. Five of six claims match the study. This overall rating is based only on the claims we could check. One claim the study doesn't address.

  • 5 supported
  • 1 not covered
Open claim evidence
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6 claims in this story

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Context layer

What the story left out

Important study details the story did not include.

  • TEE and components were measured using doubly labeled water, whole-room metabolic chamber measures, accelerometry/training reports, and subtraction-derived EEE.

    The story discusses the outcomes but does not describe the measurement stack used to obtain TEE, RMR, SMR, NEAT, and EEE.

    From Cross-sectional observational group comparison; Cross-sectional observational association analysis

  • Small sample size, including only 20 participants and 10 per menstrual-status subgroup, limits precision and statistical power.

    The story mentions need for further research on menstrual-status modification but does not report the small overall and subgroup sample sizes, an important limitation for interpreting null group differences and subgroup patterns.

    From Cross-sectional observational group comparison; Cross-sectional observational association analysis

7 things the story did carry across
  • The study was a cross-sectional observational analysis of 20 female middle- and long-distance runners, 10 amenorrhoeic and 10 non-amenorrhoeic.
  • TEE and its components did not differ between amenorrhoeic and non-amenorrhoeic runners.
  • Weekly running distance was not correlated with TEE, was negatively associated with NEAT, and was positively associated with EEE.
  • Negative associations between weekly running distance and RMR/SMR were attenuated after adjustment for body composition.
  • Similar directional associations were observed in both menstrual-status groups, but the study was not powered to test effect modification by menstrual status.
  • The observational cross-sectional design limits causal inference.
  • The abstract-depth profile provides no numerical effect sizes, confidence intervals, or p-values for the reported comparisons and associations.
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Pieces of work

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Evidence read

study summary

Lead result

human in vivo

1Lead resulthuman in vivoCompare total energy expenditure (TEE) and its components (RMR, SMR, NEAT, EEE) between amenorrhoeic and non-amenorrhoeic female endurance runners under free-living conditions.Cross-sectional observational group comparisonExpand

In plain English

In a two-group observational study of 20 female middle- and long-distance runners (10 amenorrhoeic, 10 non-amenorrhoeic), total energy expenditure (TEE) and component measures (resting metabolic rate [RMR], sleeping metabolic rate [SMR], non-exercise activity thermogenesis [NEAT], and exercise energy expenditure [EEE]) were measured using doubly labeled water (TEE, body composition), a whole-room metabolic chamber (RMR, SMR), accelerometry plus training reports (NEAT), and calculation by subtraction (EEE). The groups did not differ in TEE or its component expenditures. Weekly running distance was not correlated with TEE, was negatively associated with NEAT and positively associated with EEE, and showed negative associations with RMR and SMR that were attenuated after adjustment for body composition. Similar directional associations were observed within both menstrual-status groups, but the study was not powered to test effect modification by menstrual status. Findings were interpreted as consistent with a constrained TEE model in chronically trained runners.

Key findings

  • Total energy expenditure (TEE) and its measured components (RMR, SMR, NEAT, EEE) did not differ between amenorrhoeic and non-amenorrhoeic runners.
  • Weekly running distance was not correlated with TEE but was negatively associated with NEAT and positively associated with EEE.
“This study compared TEE components-SMR, RMR, non-exercise activity thermogenesis (NEAT), and EEE-between amenorrhoeic and non-amenorrhoeic runners”
What this piece can’t prove
  • Small sample size (n=20; 10 per group), limiting statistical power and precision.
  • Observational, cross-sectional group comparison—associations cannot establish causality.
  • Abstract provides no numerical effect sizes, confidence intervals, or p-values for reported comparisons and associations.
  • Study not powered to test effect modification by menstrual status (explicitly stated).
2human in vivoTest whether weekly running distance (training volume/physical activity) is associated with TEE and with specific TEE components (NEAT, EEE, RMR, SMR), consistent with a constrained TEE model, and assess whether associations are similar by menstrual status (exploratory).Cross-sectional observational association analysisExpand

In plain English

In 20 female middle- and long-distance runners (10 amenorrhoeic, 10 non-amenorrhoeic), weekly running distance was not correlated with total energy expenditure (TEE) but showed negative associations with non-exercise activity thermogenesis (NEAT) and positive associations with exercise energy expenditure (EEE). Negative associations between weekly running distance and resting metabolic rate (RMR) and sleeping metabolic rate (SMR) were attenuated after adjustment for body composition. TEE and its components did not differ between amenorrhoeic and non-amenorrhoeic runners, and similar directional associations by menstrual status were reported though the study was not powered to test effect modification. Findings were interpreted as consistent with a constrained TEE model.

Key findings

  • Total energy expenditure (TEE) and its components (SMR, RMR, NEAT, EEE) did not differ between amenorrhoeic and non-amenorrhoeic runners.
  • Weekly running distance was not correlated with total energy expenditure (TEE).
“examined their relationship with physical activity, particularly weekly running distance.”
What this piece can’t prove
  • Small sample size (n=20) limits precision and statistical power.
  • Study was not powered to test effect modification by menstrual status (interaction).
  • Observational cross-sectional associations limit causal inference.
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Papers considered

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PubMed, Europe PMC, Crossref · 19 candidate papers

And 13 more candidates considered.