Several possible studies
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Researchers test noninvasive ultrasound treatment for schizophrenia-related hallucinations (opens in a new tab)
news-medical.net · 2026-10-30
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Several possible studiesStudy not confirmed.
Several potential source studies were identified, but no single match could be confirmed. The article's claims remain unverified.
These papers were considered as possible sources, but none could be confirmed as the study behind this story.
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The story
Researchers test noninvasive ultrasound treatment for schizophrenia-related hallucinations
news-medical.net · 2026-10-30
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Multiple potential source studies identified.
Several studies match details in the article, but none could be confirmed as its source. The claims have not been assessed against a source study.
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Several studies could fit.
Several studies match details in the article, but none could be confirmed as its source. The claims have not been assessed against a source study.
Source layer
The 3 papers the story cites
Source study separated from background citations.
The research anchor for the report.
- Points somewhere elsepresented as the new finding
https://www.fusfoundation.org/posts/reducing-hallucinations-in-schizophrenia-with-focused-ultrasound-first-in-human-clinical-trial-begins/
- Cited as backgroundpresented as earlier work
Brain Stimulation
- Cited as backgroundpresented as earlier work
npj Acoustics
Evidence layer
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The article's claims are listed below. Without a confirmed source study, they have not been assessed as supported or unsupported.
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Claim 1 of 6Not checkedUCSF researchers, led by Karuna Subramaniam, PhD, have launched a first-in-human Phase 1 clinical trial to evaluate the safety and feasibility of repeated low-intensity focused ultrasound (LIFU) targeting the caudate in people with schizophrenia-related auditory hallucinations.View evidenceHide evidence
As statedfirst-in-human Phase 1; repeated LIFU sessions
Not checked
No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.
Claim 2 of 6Not checkedThe trial plans to enroll up to 12 participants, with five daily active LIFU sessions and five sham sessions separated by a washout period, and will compare the two conditions to assess whether active treatment reduces hallucinations beyond placebo or nonspecific effects.View evidenceHide evidence
As statedup to 12 participants; five daily sessions of each condition
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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.
Claim 3 of 6Not checkedThe study will assess resting-state functional MRI connectivity, validated hallucination measures, other psychiatric symptoms, mood, safety, tolerability, and potential side effects.View evidenceHide evidence
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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.
Claim 4 of 6Not checkedThe story says earlier preliminary findings published in Brain Stimulation found that a single LIFU session produced significant but temporary reductions in hallucinations.View evidenceHide evidence
As statedsingle session; significant, albeit temporary reductions
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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.
Claim 5 of 6Not checkedThe article says early participants in the ongoing trial have reported reductions in hallucinations after repeated LIFU, but it describes these observations as preliminary and encouraging.View evidenceHide evidence
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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.
Claim 6 of 6Not checkedThe story notes that a similar clinical trial published in npj Acoustics at NYU Langone Health used a different focused ultrasound device to target the globus pallidus in patients with schizophrenia or schizoaffective disorder and reported a modest but clear reduction in delusions.View evidenceHide evidence
As statedmodest but clear reduction in delusions
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No source study was confirmed for this article. This claim remains unverified, rather than assessed as supported or unsupported.
Method layer
Study not confirmed.
The search results are available for you to inspect. Without a confirmed source study, they cannot establish whether the story’s claims are supported or contradicted.
Search results
Candidate papers, not confirmed sources.
PubMed, Europe PMC, Crossref · 15 candidate papers
First-in-human low-intensity focused ultrasound targeting striatal circuits in schizophrenia: feasibility, safety, and effects on hallucinations and striatal-temporal functional connectivity.
medRxiv : the Preprint Server for Health Sciences · 2026 · PubMed, Europe PMC, Crossref
Effectiveness of cognitive therapy with coping training for persistent auditory hallucinations in schizophrenia: A randomised clinical trial
Schizophrenia Research · 2000 · Crossref
Focused ultrasound neuromodulation for psychiatric disorders: a scoping review of clinical applications and current progress.
2026 · Europe PMC
Brain Markers of Clinical Response to rTMS for Auditory Hallucinations in Schizophrenia.
2018 · Crossref
Neurosurgical neuromodulation therapy for psychiatric disorders.
2024 · Europe PMC