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Source study found

Story checked

Researchers develop versatile genetic tool to investigate cell interactions (opens in a new tab)

news-medical.net · 2026-10-27

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Short answer

Not assessed

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We found a likely source study, but its evidence could not be prepared for claim review. The article's claims remain unverified.

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Source study identified.

A source study was identified, but the study's evidence could not be prepared for claim assessment. No claim verdicts are available.

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Evidence layer

Claim by claim

A source study was identified, but the study's evidence could not be prepared for claim assessment. The claims below have not been assessed.

Claim 1 of 5Not checkedResearchers at the National Institute of Genetics in Japan developed a new binary gene expression system based on the bacteriophage-derived DNA-binding protein Cro and its target DNA sequence, OR3.View evidenceHide evidence

Not checked

A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.

Claim 2 of 5Not checkedThe new system, called Cro/OR3, used Cro fused to the F2 transcriptional activation domain, and CroF2 induced expression of a target gene downstream of OR3 in both zebrafish and human cultured cells.View evidenceHide evidence

Not checked

A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.

Claim 3 of 5Not checkedBy combining Cro/OR3 with the conventional Gal4/UAS system in zebrafish, the researchers were able to independently control gene expression in two distinct cell types: neurons and astrocytes.View evidenceHide evidence

Not checked

A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.

Claim 4 of 5Not checkedUsing the Cro/OR3 system, the researchers expressed in astrocytes a mutant form of Slc1a3b associated with episodic ataxia type 6, and the manipulation altered the positioning of motor neurons labeled by the Gal4/UAS system in the spinal cord.View evidenceHide evidence

Not checked

A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.

Claim 5 of 5Not checkedThe article says the team generated enhancer-trap zebrafish lines that express CroF2 in specific cell populations and that more than 150 Cro lines have been established and made available through an online resource.View evidenceHide evidence

As statedmore than 150

Not checked

A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.

Finally, the search trail

Method layer

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Open the paper in Tessa

An orthogonal Cro/OR3 system reveals an influence of astrocytes on motor neuron positioning

iScience · 2026

Source record (opens in a new tab)

Why this one

Near certain

NewsLink found the paper. Tessa is where you inspect it deeply.

Papers considered

The selected paper, plus nearby candidates.

Crossref, Europe PMC, PubMed · 38 candidate papers

Selected

An orthogonal Cro/OR3 system reveals an influence of astrocytes on motor neuron positioning

iScience · 2026 · Crossref

Source (opens in a new tab)
Candidate

Author response for "Anion Flexibility Enhances Ionic Transport and Supercooled Liquid Stability in Multicomponent Lithium Molten Salts"

2026 · Crossref

Source (opens in a new tab)

And 32 more candidates considered.