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Rapid low-cost diagnosis within reach for tuberculosis 'missed millions,' researchers find (opens in a new tab)
medicalxpress.com · 2026-10-07
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Rapid low-cost diagnosis within reach for tuberculosis 'missed millions,' researchers find
medicalxpress.com · 2026-10-07
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Diagnostic performance and testing costs of pooled testing for molecular detection of tuberculosis in seven countries: a prospective, observational, diagnostic accuracy study
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Diagnostic performance and testing costs of pooled testing for molecular detection of tuberculosis in seven countries: a prospective, observational, diagnostic accuracy study
The Lancet Global Health · 2026
- The study this story reportspresented as the new finding
Diagnostic performance and testing costs of pooled testing for molecular detection of tuberculosis in seven countries: a prospective, observational, diagnostic accuracy study
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Claim 1 of 6Not checkedResearchers say the study is the largest-ever study of pooled tuberculosis testing, carried out by Start4All, a partnership led by LSTM with the Stop TB Partnership and research partners in seven high-burden countries.View evidenceHide evidence
As statedlargest-ever study
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Claim 2 of 6Not checkedThe study found that pooled sputum testing, which examines samples from several people in a single molecular test cartridge, halves the number of cartridges needed to make successful diagnoses.View evidenceHide evidence
As statedhalves the number of cartridges needed
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Claim 3 of 6Not checkedThe paper on pooled testing performance and costs was published in The Lancet Global Health, and the first author said it could increase access to accurate, rapid and low-cost TB testing.View evidenceHide evidence
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Claim 4 of 6Not checkedThe findings reportedly informed WHO guidelines on pooled testing issued earlier this year, which recommended the technique for adolescents and adults in resource-constrained settings.View evidenceHide evidence
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Claim 5 of 6Not checkedBetween November 2023 and February 2025, more than 14,000 people with TB symptoms in Bangladesh, Brazil, Cameroon, Kenya, Malawi, Nigeria and Vietnam took part, and pooled testing used just over 7,000 cartridges instead of about 14,000, a 51% reduction, with cost per test falling from nearly $8 to less than $4.View evidenceHide evidence
As stated51% reduction; nearly $8 to less than $4
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Claim 6 of 6Not checkedThe article says pooled testing had a slight 3.1% drop in sensitivity compared with individual testing, mostly in specimens with very low TB bacterial load.View evidenceHide evidence
As stated3.1% drop in sensitivity
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Diagnostic performance and testing costs of pooled testing for molecular detection of tuberculosis in seven countries: a prospective, observational, diagnostic accuracy study
The Lancet Global Health · 2026
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Papers considered
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Crossref, Europe PMC, PubMed · 41 candidate papers
Diagnostic performance and testing costs of pooled testing for molecular detection of tuberculosis in seven countries: a prospective, observational, diagnostic accuracy study
The Lancet Global Health · 2026 · Crossref
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The Lancet Global Health · 2026 · Crossref
From DOTS to DOST: a new framework for TB elimination in India.
2026 · Europe PMC
Tuberculosis at a crossroads
The Lancet Global Health · 2026 · Crossref
And 35 more candidates considered.