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New project explores mitochondrial evolution across diverse life forms (opens in a new tab)

news-medical.net · 2026-10-01

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Claim 1 of 10Not checkedA research consortium generated the broadest look yet at the proteins that make up mitochondria across multiple branches of complex life.View evidenceHide evidence

As statedbroadest look yet

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Claim 2 of 10Not checkedThe consortium produced mitochondrial proteomes for one plant and five single-celled pathogens that affect millions of people globally every year.View evidenceHide evidence

As statedone plant and five single-celled pathogens

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Claim 3 of 10Not checkedThe results reveal unexpected new functions of the organelle, clues to its origin and role in the evolution of eukaryotes, and potential new drug targets for neglected tropical diseases.View evidenceHide evidence

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Claim 4 of 10Not checkedThe article says the findings appear in nine scientific papers and a commentary article in Cell and related journals.View evidenceHide evidence

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Claim 5 of 10Not checkedOne analysis used the new data to reconstruct the timeline of organelle emergence and supports the notion that mitochondria appeared relatively late, after the ancestral eukaryote had already developed other complex parts.View evidenceHide evidence

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Claim 6 of 10Not checkedThe article says one study catalogued Giardia mitochondria and found only 59 proteins, with no energy-producing capabilities, making it a remnant mitochondrion.View evidenceHide evidence

As stated59 proteins

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Claim 7 of 10Not checkedAnother study developed methods to study Babesia mitochondria, and those methods may also work for related pathogens such as those that cause malaria and toxoplasmosis.View evidenceHide evidence

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Claim 8 of 10Not checkedThe Acanthamoeba analysis found the most complicated energy-producing machinery of any organism described in the story, and experiments suggested its mitochondria can switch between aerobic and anaerobic respiration depending on oxygen conditions.View evidenceHide evidence

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Claim 9 of 10Not checkedThe Arabidopsis inventory is described as the most comprehensive and accurate plant mitochondrial proteome to date and as an approach that could likely work for other plants.View evidenceHide evidence

As statedmost comprehensive and accurate

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Claim 10 of 10Not checkedAn analysis of Leishmania and Trypanosoma revealed mitochondrial proteomes 50 percent larger than that of humans and containing proteins unique to those parasite classes.View evidenceHide evidence

As stated50 percent larger than that of humans

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Comparative analysis of mitochondrial proteomes across the tree of life

Cell · 2026

Source record (opens in a new tab)

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Papers considered

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Crossref, Europe PMC, PubMed · 39 candidate papers

Candidate

A0728 B cell recruitment by CCL21⁺ CAFs drives TLS maturation via the CCL21-CCR7 axis in penile squamous cell carcinoma

European Urology · 2026 · Crossref

Source (opens in a new tab)
Candidate

Author response for "Intensified lentiviral vector perfusion bioprocessing with a spiral inertial microfluidic cell retention device"

2026 · Crossref

Source (opens in a new tab)

And 33 more candidates considered.