Source study found
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New drug effectively decreases recurrence of and death from endometrial cancer (opens in a new tab)
news-medical.net · 2026-10-26
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We found a likely source study, but its evidence could not be prepared for claim review. The article's claims remain unverified.
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New drug effectively decreases recurrence of and death from endometrial cancer
news-medical.net · 2026-10-26
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Source study identified.
A source study was identified, but the study's evidence could not be prepared for claim assessment. No claim verdicts are available.
View article claimsThe source study
Sacituzumab tirumotecan versus treatment of physician's choice in previously treated endometrial cancer (TroFuse-005/ENGOT-en23/GOG-3095): a randomised, open-label, phase 3 trial
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Claim 1 of 6Not checkedA new drug, sacituzumab tirumotecan (sac-TMT), is effective at decreasing recurrence of and death from endometrial cancer, according to a landmark international study.View evidenceHide evidence
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 2 of 6Not checkedThe study compared sac-TMT with standard chemotherapy in women who had already been treated with chemotherapy and then immunotherapy for advanced or recurring endometrial cancer.View evidenceHide evidence
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 3 of 6Not checkedIn the phase 3 trial, 386 women assigned to sac-TMT had a 41 percent lower risk of progression than 390 women treated with chemotherapy alone after immunotherapy, and the risk of death was 32 percent lower.View evidenceHide evidence
As stated41 percent lower risk of progression; 32 percent lower risk of death
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 4 of 6Not checkedMore women treated with sac-TMT responded to treatment than those given standard chemotherapy, with response rates of 35.1 percent versus 17.3 percent.View evidenceHide evidence
As stated35.1 percent versus 17.3 percent
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 5 of 6Not checkedThe most frequent side effects in the sac-TMT group were low blood counts, mouth inflammation, and dry or itchy eyes, which the researchers said were manageable.View evidenceHide evidence
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 6 of 6Not checkedStudy investigators said the results support sac-TMT as a new standard treatment in recurrent endometrial cancer and may prompt guideline reassessment.View evidenceHide evidence
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Method layer
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Sacituzumab tirumotecan versus treatment of physician's choice in previously treated endometrial cancer (TroFuse-005/ENGOT-en23/GOG-3095): a randomised, open-label, phase 3 trial
The Lancet · 2026
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Papers considered
The selected paper, plus nearby candidates.
Crossref, PubMed, Europe PMC · 39 candidate papers
Sacituzumab tirumotecan versus treatment of physician's choice in previously treated endometrial cancer (TroFuse-005/ENGOT-en23/GOG-3095): a randomised, open-label, phase 3 trial
The Lancet · 2026 · Crossref
Challenges in the use of the European Society for Radiotherapy and Oncology-European Organisation for Research and Treatment of Cancer oligometastatic disease classification system in ovarian cancer.
The Lancet. Oncology · 2026 · PubMed, Crossref
PROD_EM_SUBMISSION D
2026 · Crossref
Publication and Retraction Activity in the Field of Extracorporeal Membrane Oxygenation: Origins, Concerns, and Perspectives.
2026 · Europe PMC
Consensus statements from the first Gynecologic Cancer InterGroup Cervical Cancer Consensus Conference in Clinical Research.
The Lancet. Oncology · 2026 · PubMed
Thank you to The Lancet Regional Health – Europe's clinical and statistical peer reviewers in 2025
2026 · Europe PMC
And 33 more candidates considered.