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New clinical guidelines standardize kidney replacement therapy in ICU patients (opens in a new tab)

news-medical.net · 2026-09-17

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The source study

Clinical practice guideline for renal replacement therapy in critically ill patients with acute kidney injury (2026 edition)

Journal of Intensive Medicine · 2026
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Then inspect each claim

Evidence layer

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The source study was found, but the study's evidence could not be profiled, so these claims couldn't be checked.

Claim 1 of 6Not checkedNew clinical practice guidelines standardize renal replacement therapy for adult critically ill patients with acute kidney injury in the ICU.View evidenceHide evidence

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The source study was found, but this claim couldn't be checked against it.

Claim 2 of 6Not checkedThe guideline was developed by the Chinese Society of Critical Care Medicine using a multidisciplinary panel, systematic literature retrieval, meta-analysis, evidence-based synthesis, and the GRADE approach.View evidenceHide evidence

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The source study was found, but this claim couldn't be checked against it.

Claim 3 of 6Not checkedThe guideline includes 34 recommendations across seven domains and 29 clinical questions, covering timing of initiation, vascular access, treatment modality, specialized membrane filters, anticoagulation, replacement fluids, dose, and weaning.View evidenceHide evidence

As stated34 recommendations across seven domains and 29 clinical questions

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The source study was found, but this claim couldn't be checked against it.

Claim 4 of 6Not checkedFor CRRT anticoagulation, regional citrate anticoagulation is strongly recommended first-line for patients without bleeding risk, heparin is strongly recommended first-line for patients without bleeding risk but at risk of citrate accumulation, and RCA is strongly recommended first-line for patients with bleeding risk.View evidenceHide evidence

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The source study was found, but this claim couldn't be checked against it.

Claim 5 of 6Not checkedThe guideline recommends starting RRT as early as possible in AKI patients with life-threatening fluid overload, electrolyte disturbances, or acid-base imbalances, and not delaying it when blood urea nitrogen is over 40 millimolars per liter or there is uremic encephalopathy.View evidenceHide evidence

As statedblood urea nitrogen levels over 40 millimolars per liter

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The source study was found, but this claim couldn't be checked against it.

Claim 6 of 6Not checkedThe recommendations say either continuous RRT or intermittent RRT may be selected based on clinical condition and treatment goals, and urine output recovery is suggested as a reference criterion for trial discontinuation.View evidenceHide evidence

As statedover 600 mL in 24 h on the day prior, or over 1000 mL in 24 h on the day of liberation

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The source study was found, but this claim couldn't be checked against it.

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Clinical practice guideline for renal replacement therapy in critically ill patients with acute kidney injury (2026 edition)

Journal of Intensive Medicine · 2026

Source record (opens in a new tab)

Why this one

Near certain

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Papers considered

The selected paper, plus nearby candidates.

Crossref, PubMed, Europe PMC · 16 candidate papers

Selected

Clinical practice guideline for renal replacement therapy in critically ill patients with acute kidney injury (2026 edition)

Journal of Intensive Medicine · 2026 · Crossref

Source (opens in a new tab)
Candidate

Timing of Initiation of Kidney Replacement Therapy in Acute Kidney Injury in the Critically Ill Patient

Updates on Renal Replacement Therapy · 2024 · Crossref

Source (opens in a new tab)

And 10 more candidates considered.