Several possible studies
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NAD Therapy for Addiction: What to Know (opens in a new tab)
webmd.com · 2026-05-20
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Several possible studiesNo clear answer.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
Checked against the study summary. The full text wasn't available, so some details couldn't be settled either way.
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The story
NAD Therapy for Addiction: What to Know
webmd.com · 2026-05-20
The story’s checkable claims.
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Several studies could be the source of this story.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
Open claim evidenceSearch result
Several studies could fit.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
Evidence layer
Claim by claim
What the story asserts. With no source study, there is nothing to check these against.
Reading mode
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Claim 1 of 7Not checkedCenters offering NAD therapy say it can help with withdrawal symptoms and cravings, and may suggest it could help with substance use disorders instead of, or along with, approved medicines.View evidenceHide evidence
Not checked
NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 2 of 7Not checkedNAD therapy is described as giving patients NAD, usually by intravenous infusion over multiple hours for several days, or sometimes as a pill containing NAD or a precursor.View evidenceHide evidence
Not checked
NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 3 of 7Not checkedThe article says there are not many published studies showing whether NAD therapy works, and that it is not proven or approved for any use, including addiction treatment.View evidenceHide evidence
Not checked
NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 4 of 7Not checkedThe first study testing NAD for substance use disorders reportedly gave IV NAD to more than 100 people with alcohol use disorder, opioid use disorder, or other substance use disorders.View evidenceHide evidence
As statedmore than 100 people
Not checked
NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 5 of 7Not checkedMore recent data are said to suggest that NAD therapy is safe and might help, but the article says it still has not been tested or proven in enough people to know whether it works or how well.View evidenceHide evidence
As stated800 to 1,800 milligrams a day over 3 to 8 hours every day for at least a week
Not checked
NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 6 of 7Not checkedAnother study is described as showing that IV infusion of NAD increases NAD levels at 750 milligrams for 6 hours, without observed adverse effects, while leaving open what happens to NAD in the body.View evidenceHide evidence
As stated750 milligrams for 6 hours
Not checked
NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 7 of 7Not checkedThe article concludes that it remains uncertain whether and how much NAD therapy helps substance use disorders, withdrawal symptoms, or any other condition, and says companies and clinics should not market it as a proven treatment for those uses.View evidenceHide evidence
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Method layer
No single source study was found.
NewsLink still surfaces nearby research so you can inspect the field instead of a single paper.
Nearby research
No exact source, but these papers are close.
PubMed, Crossref, Europe PMC · 15 candidate papers
Narrative review of intravenous NAD+ and NAD+ precursors in wellness and translational medicine.
Frontiers in Aging · 2026 · PubMed
ß-Nicotinamide Adenine Dinucleotide
Crossref
A phase-II randomized controlled pilot study of nicotinamide riboside supplementation in older adults with amnestic mild cognitive impairment.
2026 · Europe PMC
Mitochondrial dysfunction drives metabolic reprogramming in Gitelman syndrome: insights from proteomics and isogenic modeling.
Human Genetics · 2026 · PubMed
Nicotinamide adenine dinucleotide-dependent enzymatic mechanisms and nicotinamide adenine dinucleotide precursors (nicotinamide mononucleotide, nicotinamide riboside)
Unlocking Sirtuins · 2026 · Crossref
And 10 more candidates considered.