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Microplastics clog liver immune cells, driving fat buildup in mice (opens in a new tab)

medicalxpress.com · 2026-09-29

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Claim 1 of 6Not checkedMicroplastics appear capable of significantly impairing the function of liver phagocytes in mice.View evidenceHide evidence

As statedsignificantly

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The source study was found, but this claim couldn't be checked against it.

Claim 2 of 6Not checkedThe macrophage stress response led surrounding liver cells to store more fat, increasing fat buildup in the liver.View evidenceHide evidence

As statedmore fat

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Claim 3 of 6Not checkedIn mice, orally administered microplastics were taken up in large amounts by Kupffer cells in the liver after 12 weeks.View evidenceHide evidence

As statedlarge amounts

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Claim 4 of 6Not checkedPlastic particles clogged macrophage lysosomes, reducing their ability to take up pathogens or defective cells and disrupting their metabolism.View evidenceHide evidence

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The source study was found, but this claim couldn't be checked against it.

Claim 5 of 6Not checkedParticles that were 10 times smaller had less pronounced macrophage clogging, left liver metabolism largely unchanged, and instead accumulated in brown adipose tissue, where they stimulated heat production.View evidenceHide evidence

As stated10 times smaller

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Claim 6 of 6Not checkedThe study was published in Nature Metabolism and is identified as a joint German-Austrian study led by the University of Bonn.View evidenceHide evidence

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Open the paper in Tessa

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism

Nature Metabolism · 2026

Source record (opens in a new tab)

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Papers considered

The selected paper, plus nearby candidates.

Crossref, Europe PMC, PubMed · 40 candidate papers

Selected

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism

Nature Metabolism · 2026 · Crossref

Source (opens in a new tab)
Candidate

Future Educational and Occupational Concerns and Career Decision-Making Among Secondary School Students

International Journal of Business and Management Invention · 2026 · Crossref

Source (opens in a new tab)
Candidate

Author Correction: Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis

Nature Metabolism · 2026 · Crossref

Source (opens in a new tab)

And 34 more candidates considered.