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Greater variation in blood pressure associated with higher risk of death and strokes (opens in a new tab)
news-medical.net · 2026-09-29
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Greater variation in blood pressure associated with higher risk of death and strokes
news-medical.net · 2026-09-29
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Open claim evidenceThe source study
Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study
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Claim 1 of 8Not checkedGreater variation in blood pressure between research visits was associated with a higher risk of death in a study of more than 57,000 UK Biobank participants.View evidenceHide evidence
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The source study was found, but this claim couldn't be checked against it.
Claim 2 of 8Not checkedVariation in some blood pressure measures was also associated with strokes.View evidenceHide evidence
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The source study was found, but this claim couldn't be checked against it.
Claim 3 of 8Not checkedThe study, led by Dr. Fariba Ahmadizar at Amsterdam University Medical Center, included 57,611 participants, with a median follow-up of 5.1 years and 1,460 deaths, 571 strokes, and 319 dementia cases reported during follow-up.View evidenceHide evidence
As stated57,611 participants; 5.1 years median follow-up; 1,460 deaths; 571 strokes; 319 dementia cases
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The source study was found, but this claim couldn't be checked against it.
Claim 4 of 8Not checkedGreater variability in each of the four blood pressure measures studied was associated with a higher risk of death from any cause, even after adjusting for average blood pressure, blood sugar status and other factors.View evidenceHide evidence
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The source study was found, but this claim couldn't be checked against it.
Claim 5 of 8Not checkedEach one standard deviation increase in systolic blood pressure variability was associated with an 11% higher risk of death, and the corresponding increase was 8% for diastolic blood pressure variability.View evidenceHide evidence
As stated11% higher risk of death; 8% higher risk of death
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The source study was found, but this claim couldn't be checked against it.
Claim 6 of 8Not checkedGreater variability in diastolic blood pressure and mean arterial pressure was also associated with strokes, with likelihoods 12% and 10% higher, respectively, for each one-standard-deviation increase in variability.View evidenceHide evidence
As stated12% higher; 10% higher
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The source study was found, but this claim couldn't be checked against it.
Claim 7 of 8Not checkedCompared with participants with normal blood sugar and low systolic blood pressure variability, those with type 2 diabetes and high systolic blood pressure variability were almost three times more likely to die during follow-up, and those with prediabetes plus high variability had a 62% higher risk of death.View evidenceHide evidence
As stated2.8 times; 62% higher
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Claim 8 of 8Not checkedNo statistically significant associations were found for dementia, and the authors said the observational study did not prove causality.View evidenceHide evidence
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Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study
Cerebral Circulation - Cognition and Behavior · 2025
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Papers considered
The selected paper, plus nearby candidates.
PubMed, Crossref, Europe PMC · 15 candidate papers
Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study
Cerebral Circulation - Cognition and Behavior · 2025 · Crossref
Multivariate GWAS framework for family trios with parental phenotypes to control dynastic effects.
BMC Bioinformatics · 2026 · PubMed
Kidney function and brain health: cognitive and structural signatures across cohorts.
2026 · Europe PMC
Irritable Bowel Syndrome and Incident Hypertension: Epidemiologic and Genetic Insights.
Biomedicines · 2026 · PubMed
Clinical Feasibility and Other Necessary Considerations of Visit-to-Visit Blood Pressure Variability
Comment Group · 2023 · Crossref
Living alone, long-term cardiometabolic stability, and medication management in adults with type 2 diabetes: a secondary analysis of the ACCORD trial.
2026 · Europe PMC
And 9 more candidates considered.