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Fluctuations in blood pressure over time linked to death and strokes, analysis of UK data finds (opens in a new tab)

medicalxpress.com · 2026-09-28

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The source study

Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study

Cerebral Circulation - Cognition and Behavior · 2025
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Claim 1 of 5Not checkedGreater variation in blood pressure between research visits was associated with a higher risk of death in a study of more than 57,000 UK Biobank participants.View evidenceHide evidence

As statedhigher risk of death

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Claim 2 of 5Not checkedVariation in some blood pressure measures was also associated with stroke.View evidenceHide evidence

As statedassociated with stroke

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Claim 3 of 5Not checkedParticipants with both high variation in systolic blood pressure and diabetes had nearly three times the risk of death from any cause compared with participants who had normal blood sugar and low variation.View evidenceHide evidence

As statednearly three times the risk of death; 2.8 times as likely to die

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Claim 4 of 5Not checkedThe researchers said blood pressure variability is not routinely taken into account in assessing health, and that the results suggest it could help identify high-risk patients who might otherwise be overlooked.View evidenceHide evidence

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Claim 5 of 5Not checkedThe study was observational, so it did not prove causality, and the authors said more research is needed before blood pressure variability can be recommended for routine clinical use.View evidenceHide evidence

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Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study

Cerebral Circulation - Cognition and Behavior · 2025

Source record (opens in a new tab)

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Papers considered

The selected paper, plus nearby candidates.

PubMed, Europe PMC, Crossref · 15 candidate papers

Selected

Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study

Cerebral Circulation - Cognition and Behavior · 2025 · Crossref

Source (opens in a new tab)
Candidate

Clinical Feasibility and Other Necessary Considerations of Visit-to-Visit Blood Pressure Variability

Comment Group · 2023 · Crossref

Source (opens in a new tab)

And 9 more candidates considered.