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Brain circuit linked to food cravings during pregnancy identified (opens in a new tab)

medicalxpress.com · 2026-09-18

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Claim 1 of 5Not checkedResearchers at LSU's Pennington Biomedical Research Center and collaborators identified a brain mechanism that may help explain how pregnancy changes motivation to seek certain highly palatable foods.View evidenceHide evidence

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Claim 2 of 5Not checkedThe study, published in Nature Neuroscience, found that serotonin neurons in the dorsal raphe nucleus become less active during pregnancy, increasing food-craving-like behavior in animal models.View evidenceHide evidence

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Claim 3 of 5Not checkedActivity of the SK3 potassium ion channel increases in serotonin neurons during pregnancy; removing SK3 from these neurons prevented the pregnancy-associated reduction in neuronal activity and substantially reduced food-craving-like behavior, while increasing SK3 activity in nonpregnant females produced pregnancy-like changes in food-seeking behavior.View evidenceHide evidence

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Claim 4 of 5Not checkedThe team identified a neural pathway from dorsal raphe serotonin neurons to the ventral tegmental area; activating the pathway reduced food-craving-like behavior in pregnant animals, while inhibiting it increased the behavior in nonpregnant animals.View evidenceHide evidence

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Claim 5 of 5Not checkedThe article says the findings are currently based on animal studies, and that further research, including human clinical studies, is needed before considering translation to prevention of maternal obesity.View evidenceHide evidence

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Serotonin neurons in the dorsal raphe control food-craving-like behavior during pregnancy in mice

Nature Neuroscience · 2026

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Papers considered

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Crossref, PubMed, Europe PMC · 40 candidate papers

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Serotonin neurons in the dorsal raphe control food-craving-like behavior during pregnancy in mice

Nature Neuroscience · 2026 · Crossref

Source (opens in a new tab)
Candidate

Author response for "Structural Optimization and Experimental Analysis of Vortex Gripper for Breathable Garment Pieces"

2026 · Crossref

Source (opens in a new tab)
Candidate

Author response for "A Metal-Organic Framework Ce-BDA for Triple-Modal Cancer Therapy: Chemodynamic Therapy, Chemotherapy and Immunotherapy"

2026 · Crossref

Source (opens in a new tab)

And 34 more candidates considered.