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Blood biomarkers help track gut pathology in celiac disease (opens in a new tab)

news-medical.net · 2026-10-08

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Claim 1 of 6Not checkedA new study investigated whether proteins in the blood could serve as biomarkers of celiac disease activity.View evidenceHide evidence

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Claim 2 of 6Not checkedThe researchers analyzed 264 blood and tissue samples from people with celiac disease before treatment and after one year on a gluten-free diet, plus samples from people without celiac disease.View evidenceHide evidence

As stated264 samples

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Claim 3 of 6Not checkedUsing proteomics, the team identified 24 proteins associated with celiac disease, and nine of them were particularly linked to the extent of intestinal damage.View evidenceHide evidence

As stated24 proteins; 9 particularly linked

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Claim 4 of 6Not checkedUntreated celiac disease had the highest levels of inflammatory proteins, healthy individuals had the lowest, and protein levels changed before and after treatment, suggesting blood proteins may reflect inflammation and healing in the gut.View evidenceHide evidence

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Claim 5 of 6Not checkedThe article says people with celiac disease who followed a gluten-free diet still had slightly higher levels of some proteins than healthy individuals, suggesting some gut inflammation may persist despite diet.View evidenceHide evidence

As statedslightly higher levels

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Claim 6 of 6Not checkedThe researchers hope tests based on the newly identified biomarkers could eventually complement existing methods for monitoring celiac disease, but further studies in more patients are needed before clinical use.View evidenceHide evidence

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PubMed, Europe PMC, Crossref · 36 candidate papers

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