Several possible studies
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Algorithmic tool may improve screening of patients for an Alzheimer's clinical trial (opens in a new tab)
medicalxpress.com · 2026-09-09
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Several possible studiesNo clear answer.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
Checked against the study summary. The full text wasn't available, so some details couldn't be settled either way.
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Algorithmic tool may improve screening of patients for an Alzheimer's clinical trial
medicalxpress.com · 2026-09-09
The story’s checkable claims.
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Several studies could be the source of this story.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
Open claim evidenceSearch result
Several studies could fit.
More than one paper fits the article's details, and none fits well enough to single out. Checking claims against the wrong study would be worse than not checking them at all.
Evidence layer
Claim by claim
What the story asserts. With no source study, there is nothing to check these against.
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Claim 1 of 4Not checkedA new blood-based screening algorithm dramatically reduced the number of unnecessary PET scans needed to recruit patients at risk of Alzheimer's disease for a clinical trial, according to research from scientists at the Keck School of Medicine of USC published in Alzheimer's & Dementia.View evidenceHide evidence
As stateddramatically reduced
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 2 of 4Not checkedWhen the algorithm was used to recruit participants, it cut the rate of people who received a PET scan but did not qualify for the trial from more than 70% to 31%.View evidenceHide evidence
As statedfrom more than 70% to 31%
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 3 of 4Not checkedThe AHEAD 3-45 clinical trial is a phase 3 international study testing whether earlier treatment with lecanemab could lead to better outcomes in people with amyloid-beta buildup before symptoms appear.View evidenceHide evidence
As statedphase 3 international study
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Claim 4 of 4Not checkedThe screening tool incorporated amyloid-beta ratio, p-tau217, age, and APOE4 carrier status, and was developed using data from 1,080 AHEAD participants and validated in an independent dataset from the Wisconsin Registry for Alzheimer's Prevention study.View evidenceHide evidence
As stated1,080 AHEAD participants
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NewsLink could not identify one source study, so this claim was not compared against a paper.
Method layer
No single source study was found.
NewsLink still surfaces nearby research so you can inspect the field instead of a single paper.
Nearby research
No exact source, but these papers are close.
PubMed, Crossref, Europe PMC · 15 candidate papers
Plasma Aβ42/Aβ40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association · 2024 · PubMed
Plasma p-Tau217 and Aβ42/40 for identifying amyloid PET positivity in cognitively unimpaired asian individuals: A systematic review and meta-analysis
Ageing Research Reviews · 2026 · Crossref
Racial and ethnic differences in plasma p-tau217 ratio biomarker eligibility rates in a preclinical AD trial with lecanemab.
2025 · Europe PMC
Gel electrophoretic distinction between Congo Red nonreactive beta-amyloid (1—42) and beta-amyloid (1—40)
Electrophoresis · 2000 · Crossref
Biomarkers, diagnosis, and the meaning of disease: evaluating competing frameworks for Alzheimer's disease classification.
2026 · Europe PMC
And 10 more candidates considered.