Source study found
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Adding a Mirena IUD during surgery can reduce the risk of hysterectomy in women with heavy menstrual bleeding (opens in a new tab)
medicalxpress.com · 2026-10-22
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We found a likely source study, but its evidence could not be prepared for claim review. The article's claims remain unverified.
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Adding a Mirena IUD during surgery can reduce the risk of hysterectomy in women with heavy menstrual bleeding
medicalxpress.com · 2026-10-22
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Source study identified.
A source study was identified, but the study's evidence could not be prepared for claim assessment. No claim verdicts are available.
View article claimsThe source study
Endometrial ablation plus levonorgestrel-releasing intrauterine system versus endometrial ablation alone in women with heavy menstrual bleeding in The Netherlands (MIRA2): a multicentre, open-label, randomised, controlled, superiority trial
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A source study was identified, but the study's evidence could not be prepared for claim assessment. The claims below have not been assessed.
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Claim 1 of 5Not checkedFitting a hormonal IUD during surgery for heavy menstrual bleeding reduces the risk of needing a hysterectomy in the following two years by more than half, according to a new open-label randomized controlled trial published in The Lancet.View evidenceHide evidence
As statedmore than half
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 2 of 5Not checkedThe MIRA2 trial tested whether fitting a hormonal IUD during an endometrial ablation could reduce the need for a hysterectomy in the future.View evidenceHide evidence
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 3 of 5Not checkedResearchers followed 715 women at 34 hospitals in the Netherlands for two years; about 4% of women who had an IUD fitted needed a hysterectomy, compared with 10% of those who had ablation alone.View evidenceHide evidence
As statedabout 4% versus 10%
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 4 of 5Not checkedWomen given an IUD also had better bleeding and pain outcomes, including more frequent amenorrhea at six months, less need for additional medication over two years, and less cyclical period pain at two years.View evidenceHide evidence
As stated59% versus 46%; 6% versus 16%; 17% versus 25%
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Claim 5 of 5Not checkedThe authors said hormonal IUD insertion during endometrial ablation could prevent future hysterectomies and improve bleeding and pain control, but side effects should be included in counseling because they were commonly reported and could lead to discontinuation.View evidenceHide evidence
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A source study was identified, but the evidence comparison for this claim was not completed. No verdict has been assigned.
Method layer
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Endometrial ablation plus levonorgestrel-releasing intrauterine system versus endometrial ablation alone in women with heavy menstrual bleeding in The Netherlands (MIRA2): a multicentre, open-label, randomised, controlled, superiority trial
The Lancet · 2026
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Papers considered
The selected paper, plus nearby candidates.
Crossref, PubMed, Europe PMC · 16 candidate papers
Endometrial ablation plus levonorgestrel-releasing intrauterine system versus endometrial ablation alone in women with heavy menstrual bleeding in The Netherlands (MIRA2): a multicentre, open-label, randomised, controlled, superiority trial
The Lancet · 2026 · Crossref
Perimenopausal abnormal uterine bleeding.
Maturitas · 2024 · PubMed
Faculty Opinions recommendation of Hysterectomy, endometrial ablation, and levonorgestrel releasing intrauterine system (Mirena) for treatment of heavy menstrual bleeding: cost effectiveness analysis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2011 · Crossref
A Study of the Effect of the Levonorgestrel Intrauterine System on the Management of Abnormal Uterine Bleeding.
2025 · Europe PMC
A 52-mg levonorgestrel-releasing intrauterine system vs bipolar radiofrequency nonresectoscopic endometrial ablation in women with heavy menstrual bleeding: long-term follow-up of a multicenter randomized controlled trial.
American Journal of Obstetrics and Gynecology · 2024 · PubMed
Menorrhagia and the Levonorgestrel Intrauterine System
Hysterectomy · 2012 · Crossref
And 10 more candidates considered.